Reliance Publishing’s client list is as broad and diverse as its service offerings.

- International Franchise Association
- North Carolina Film Office
- University of Virgina Health Sciences Center
- Kappa Delta Sorority
- Sigma Nu Fraternity
- Theta Phi Alpha Fraternity
- Alpha Epsilon Phi Sorority
- LaBelle France
- Allsorts Promotional Products
- Chappell Graphics / inCharlottesville.com
- O’Leary Wealth Management
- Winfall Nurseries